The customized #Pellet #capsules #Wonder Biotech
Compared with capsule, pellet capsule have unique characteristics in terms of appearance, preparation process, and application.
1. Beautiful appearance and good fluidity. When filling capsules with pellet, no flow aid is required, and the weight difference is smaller compared to filling capsules with powder. It is commonly used to prepare compound preparations;
2. Wide drug loading range;
3. Can be used to make sustained-release formulations. The drug release rate can be obtained by mixing multiple small pellet with different release rates. The preparation of sustained-release, controlled release, or targeted release formulations using pellet coating is feasible, reliable in quality, and has good inter batch reproducibility;
4. Stable drug release. The oral administration of microspheres is less affected by gastric emptying factors, and the drug absorption rate is uniform;
5. Beneficial for drug absorption and high bioavailability.
6. It can improve the stability of drugs, such as avoiding compatibility taboos between multiple drugs and slowing down the degradation rate of drugs;
7. Reduce the irritation of drugs on the digestive tract and mask the unpleasant taste of certain drugs. After entering the body, the contact area between pellet and body fluids is larger than that of tablets and other preparations. pellet are widely distributed in the gastrointestinal tract and will not cause adverse reactions or local irritation due to excessive drug concentration.
